Electrochemical oxidation of 6-hydroxy-2,4,5- triaminopyrimidine at pyrolytic graphite electrode

The electrochemical ox idation of 6-hydroxy-2,4,5-triaminopyrimidine (I) at pyrolytic graphite electrode has been studied in phosphate buffers of pH range 2.5-10.8. Under cyclic voltammetric conditions, the 2e, 2H+ ox idation of this compound is fo und to give alloxan, which has been characterized on the basis of IR, mass and NMR spectral data. The kinetics of the decay of the UV -absorbing intermediate generated during electrooxidation of compound (I) has been studied and fi rst order rate constants for the di sappearance of UV -absorbing intermediate have been calculated. A tentative mechani sm in which electrode reaction is followed by chemical steps (EC) for the oJ\idation ofI has also been suggested.